Product details

Amitriptyline is a generic antidepressant medication designed to treat the symptoms of depression. This medication is what is known as a tricyclic antidepressant, and it works by increasing the levels of serotonin in your brain. These increased serotonin levels influence your central nervous system, or CNS, by improving your emotional state, mood, quality of sleep, and the way your body reacts to pain. While we currently don’t carry Amitriptyline, it may be worth visiting your doctor to see if it’s right for you.

Additional Details

  • Treats eating disorders
  • Prevents tension and migraine headaches
  • Decreases feelings of anxiety
  • Reduces symptoms of depression
  • Relieves post-herpetic neuralgia
  • Minimizes pain associated with arthritis or fibromyalgia
Active Ingredients
  • Amitriptyline hydrochloride
  • Do not take if you have recently had a heart attack.
  • Use with caution if you suffer from liver disease or kidney problems.
  • Use with caution if you have a history of urinary retention.
  • Do not take if you are pregnant, plan to become pregnant, or are breastfeeding.
  • Do not take if you are allergic to Amitriptyline.
  • Do not take if you have bipolar disorder.
  • Do not take if you have porphyria.
  • Do not take if you have glaucoma.
  • Use with caution if you have thoughts of suicide or self-harm.
  • Do not take if you have diabetes.
  • Do not take if you have schizophrenia.
  • Do not take if you have a history of seizures.





  • What Is Amitriptyline?

    Amitriptyline is a generic antidepressant medication designed to treat the symptoms of depression. This medication is what is known as a tricyclic antidepressant, and it works by increasing the levels of serotonin in your brain. These increased serotonin levels influence your central nervous system, or CNS, by improving your emotional state, mood, quality of sleep, and the way your body reacts to pain. While we currently don't carry Amitriptyline, it may be worth visiting your doctor to see if it's right for you.

  • How Is Amitriptyline Used?

    Amitriptyline is a pill that's usually taken between one and four times a day. You should take Amitriptyline at the same time(s) each day and exactly how it's directed by your doctor or pharmacist. Generally, doctors start patients off on a low dose of Amitriptyline and slowly increase the dosage over time. Amitriptyline should be stored at room temperature in a closed container, away from direct light, moisture, and extreme heat or cold. Because of this, it's best not to store this medication in the bathroom.

    It could take some time, a few weeks or more, to feel the full benefits of this medication. If you decide you'd like to stop taking Amitriptyline, you should discuss it with your doctor first so they can gradually decrease your dosage over time. You could experience withdrawal symptoms, such as fatigue, headache, and nausea if you abruptly stop taking this medication.

  • Is Amitriptyline Easy To Get?

    Amitriptyline is commonly prescribed as an antidepressant and migraine preventive, so it is available at a majority of pharmacies with a prescription from a doctor. Though we don't carry Amitriptyline at Nurx™, we do offer other generic antidepressants, like Nortriptyline, that also help to treat migraines. When you order through Nurx, you don't need insurance or even a prescription from your general practitioner. We have physicians in every state we work in, making it easy and painless to get the medication you need, when you need it.

  • What Precautions Should I Take Before Starting Amitriptyline?

    Before you take Amitriptyline, let your doctor and pharmacist know if you're allergic to Amitriptyline, the active ingredient, or any other medications. Additionally, you should tell your doctor about any other prescription and nonprescription medications, herbal products, supplements, and vitamins you are currently taking or have taken in the past two months as they could negatively interact with Amitriptyline.

    Amitriptyline could make you drowsy, so you should avoid operating machinery or driving a car until you've been taking it for a few days so that you know how this medication impacts you. It's also important to note that alcohol can intensify the drowsiness often experienced with this medication. If you regularly consume large amounts of alcohol, let your doctor know before taking Amitriptyline.

    Make sure that your doctor or dentist is aware that you are taking Amitriptyline before undergoing any kind of surgical procedure, and talk to your doctor if you become or plan to become pregnant before or while taking Amitriptyline. It's important that you refrain from breastfeeding while taking this medication. It's also vital that you let your doctor know if you have or have ever had:

    Liver, kidney, or heart disease.



    An overactive thyroid gland.


    Trouble urinating.

    An enlarged prostate.


  • Are There Any Known Side Effects?

    Though most people take Amitriptyline without experiencing any side effects, there are possible side effects associated with it, just like with any medication. Some of the more common side effects include constipation, headache, difficulty urinating, drowsiness, dry mouth, and dizziness. Some of the less common yet more serious side effects include:



    Changes in weight or appetite.

    Sweating excessively.

    Changes in sexual ability or desire.

    Tingling, burning, or pain in the hands or feet.

    Blurred vision.

    Pain, redness, or swelling in and around the eye.


    Fatigue or weakness.



    Thoughts of self-harm.

    Low blood pressure.


    Muscle cramps.

    Yellowing skin and/or eyes.

    Fast or irregular heartbeats.

    Trouble speaking.

    This isn't a comprehensive list of possible side effects, so you may experience a side effect that isn't listed here. If you have a symptom, like the ones listed above, that seems unusual or worrisome while taking this medication, contact your physician or seek medical help right away. A healthcare professional can determine the seriousness of the situation and provide guidance on what you should do.

  • Can I Take Amitriptyline With Other Medications?

    Just like with most medications, Amitriptyline can interact with other drugs, which is why it's vital that you tell your doctor about all of the other medications, supplements, and vitamins that you're taking. Namely, taking a monoamine oxidase (MAO) inhibitor within two weeks of taking Amitriptyline can cause significant symptoms and complications, such as convulsions, high blood pressure, high temperatures, restlessness, and confusion. Additionally, taking this medication along with Cisapride could increase the likelihood of experiencing serious side effects.

    When paired with alcohol and other central nervous system depressants, Amitriptyline could cause extreme drowsiness that lasts for several days. Because of this, it's best to avoid taking multiple CNS depressants at the same time. Some examples of CNS depressants include:


    Muscle relaxants.

    Seizure medication.



    Prescription pain medicine.

    Sleeping medicine.




  • How Do I Get a Prescription for Amitriptyline Through Nurx?

    Though we don't prescribe or sell Amitriptyline at Nurx, we do offer other generic antidepressants that can be used as migraine preventives, like Nortriptyline. Before we prescribe any medication, we have you complete an online assessment to learn a bit more about your headaches and overall health. From there, one of our doctors reviews your medical history and then develops a treatment plan that could include medication to prevent and/or stop the pain associated with migraines.

  • Can I Buy This Drug Online Through Nurx?

    You can purchase medications just like Amitriptyline from the comfort of your own home! After you take our online assessment and have a consultation with one of our doctors, you will receive a personalized treatment plan and a prescription. We make getting your medication simple and hassle-free by shipping it directly to your door.

  • How Long Would It Take To Deliver This Drug If I Bought It Online?

    We offer free one to three-day priority shipping through USPS, which means that you can expect to have your medication in your hands roughly three to five days after your prescription is filled at our pharmacy.

  • Who Makes This Drug?

    Amitriptyline is a generic drug manufactured by:

    Accord Healthcare, Inc.

    Major Pharmaceuticals.

    NorthStar Rx, LLC.


    Zydus Pharmaceuticals, Inc.

    Sandoz, Inc.

    Mylan Pharmaceuticals, Inc.

  • Does Taking Amitriptyline Make You Hungry?

    Amitriptyline has been known to have an impact on a person's appetite. In some cases, people experience increased hunger, while others experience a loss of appetite.

  • Does Amitriptyline Cause Weight Gain?

    Amitriptyline has led to weight gain in some patients, which could be attributed to the increased appetite. Other possible causes of weight gain include:

    A feeling of drowsiness is common among people taking Amitriptyline, and it could lead to a less active lifestyle.

    A change in hormone levels that regulate hunger and appetite.

    Slowed metabolism due to the changes in hormone levels and the sedative effects of the medication.

  • Can Amitriptyline Be Used To Treat Anxiety?

    Like most tricyclic antidepressants, Amitriptyline was developed to treat both depression and anxiety.

  • Can Amitriptyline Affect Blood Pressure?

    Rarely, Amitriptyline can cause spikes in blood pressure as well as QT prolongation, a condition that impacts the heart's natural rhythm.

  • Does Amitriptyline Help With Sleep?

    Amitriptyline is often prescribed to treat insomnia. One of the reasons this medication is so helpful for this off-label use is that it blocks histamines, resulting in drowsiness.

  • How Does Nurx Work?

    Nurx is a telehealth platform offering easy online access to doctors and seamless delivery of medications. No more time-consuming trips to the clinic and no more frantic pharmacy runs. We put you in control of your own health, empowering you to get the care you need, when you need it. From diagnosis to delivery of prescriptions, we make every part of getting healthy and staying healthy, better.For more information and to sign up, visit and follow us @nurxapp on Twitter and Instagram.

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