Product details

If you’re experiencing intense migraines in addition to nausea or vomiting, Ondansetron might just be the best solution for you. This medication is regularly used for patients who have just undergone surgery, chemotherapy, or radiation therapy. Patients who experience any symptoms after these surgeries will usually take this pill and feel much better. At Nurx™, our doctors usually prescribe Ondansetron alongside a different migraine medication to help treat symptoms you may get from migraines, like nausea.

Additional Details

  • Prevents nausea
  • Prevents vomiting
  • Reduces or eliminates migraines
Active Ingredients
  • Ondansetron hydrochloride dihydrate
  • Do not use if you take apomorphine.
  • Increased risk for patients with underlying heart diseases.
  • Alert your doctor of any ongoing heart conditions.
  • Do not take if you're pregnant or are trying to become pregnant unless otherwise stated by your doctor.
  • Increased risk of constipation, diarrhea, headache, rash, hiccups, fatigue, flushing.
  • Increased risk of facial swelling, blurred or loss of vision, difficulty breathing, seizures, or chest pain.
  • Do not take if you're using medication with serotonin 5-HT3 antagonists.
  • Do not take if you're using antibiotics like Clarithromycin and Erythromycin.
  • Do not take if you're using beta blockers.
  • Do not take if you're using seizure medications.
  • Do not take if you're using antipsychotic medications.





  • How Does Ondansetron Work?

    You can use Ondansetron on its own or pair it with other medications to eliminate nausea, vomiting, migraines, or any other symptom that may be causing you discomfort. It works by blocking certain chemicals in your body that might trigger nausea or vomiting, especially after you've undergone surgery, radiation treatment, or chemotherapy. It also helps to treat symptoms associated with migraines, like nausea or vomiting.

    How much Ondansetron you should take may depend on what your doctor prescribes, so be sure to read the prescription label and follow it carefully. Make sure you're not taking doses that are smaller or larger than your recommended amount. Ondansetron is available as regular or disintegrating tablets. You can chase down your regular tablet with a full glass of water or place the dissolving tablet right on the tip of your tongue to let it dissolve and mix with your saliva before swallowing.

    These pills come in a bottle or blister pack. If you receive the blister pack, dry your hands to open it and carefully peel back the foil and pop the pill in your mouth as soon as you retrieve it from the pack. The dosage your doctor prescribes usually depends on any preexisting medical conditions and whether or not you're about to go into surgery or chemotherapy. Kids can also use this medication. The doctor can prescribe a certain dosage based on their age and weight.

  • Is Ondansetron Easy to Get?

    Yes! All you need to do is complete our medical assessment and answer questions so that one of our providers can personalize a treatment plan for you. Your answers will help them determine if Ondansetron is right for you and the dosage that's well-suited for your needs. Once this is done, we'll deliver the medication to your door or we'll call the prescription into a local pharmacy for you to easily pick up.

    At Nurx, we accept several insurance providers and also offer affordable out-of-pocket pricing if you don't have insurance.

  • What Precautions Should I Take Before Starting Ondansetron?

    Be sure to speak with your doctor before taking Ondansetron and let them know of any allergies you may have. This medication has some inactive ingredients in it that might cause your allergic reactions to flare up, so be sure to let them know so they can prevent this from occurring. It's important to also inform the doctor of your medical history, especially if you have had liver disease, stomach or intestine problems, any recent surgeries, or irregular heartbeats.

    If you have heart problems or a family history of heart problems, tell your doctor and inform them of any medications you take for it. Though it's very rare, this medication has been known to cause a condition called QT prolongation that causes irregular heartbeats. As long as you let the doctors know of your medical history, they should keep you from this condition. Try to stay away from marijuana or alcohol when taking this medication, as it increases the chances of feeling extra dizzy, drowsy, or lightheaded. It's also best to refrain from driving heavy machinery if this medication is making you feel dizzy. Consult your doctor if you're pregnant or planning to become pregnant as there could be some risks involved.

  • Are There Any Known Side Effects?

    Similar to many medications, there are several mild side effects that might occur when taking Ondansetron. These include lightheadedness, drowsiness, constipation, headaches, tiredness, or dizziness. If you feel these coming on, lie down for a while and wait for them to subside. Let your doctor know immediately If these symptoms continue or worsen.

    There are also some uncommon side effects that are likely to occur, such as muscle stiffness or spasms, changes in vision, or stomach pains. Tell your doctor if you experience any of these symptoms. Some rare and serious side effects include slow, fast, or irregular heartbeat, fainting, or severe dizziness. If you experience any of these side effects, seek medical help as soon as possible.

    Ondansetron may also increase the serotonin levels in your body and could cause a rare but serious case of serotonin syndrome. Seratonin syndrome may cause symptoms like hallucinations, fast heartbeat, twitching muscles, loss of coordination, or unexplained fever. Get medical attention as soon as possible if you experience any of these. Remember that these side effects are very rare and there are many positive side effects you'll also receive when taking this medication.

  • Can I Take Ondansetron with Other Medications?

    While there are several medications that are perfectly safe to take with Ondansetron, watch out for some that aren't. Stay away from medications like apomorphine or tramadol, as these can cause a serious interaction with Ondansetron. Other medications like Pimozide, Amiodarone, Sotalol, Dofetilide, Procainamide, Quinidine, and different Macrolide antibiotics are known to affect your heart's rhythm, so avoid taking any of these with Ondansetron.

    Taking antidepressants with Ondansetron can increase the likelihood of serotonin syndrome. It's important to mention any drugs or medications you're taking when meeting with your doctor to ensure you're safe to take the proper dosage of Ondansetron.

  • How Do I Get a Prescription for Ondansetron Through Nurx?

    You can easily snag a prescription for this medication or have it delivered to your door after taking the assessment provided by our doctors. After conducting an assessment with them, they'll let you know if this is the most effective drug for you to take. If you've used this medication before and know it's worked well for you in the past, let the doctor know. They'll keep this in mind and will prescribe it to you online if it still seems right for you.

  • Can I Buy This Drug Online Through Nurx?

    You can purchase Ondansetron online after receiving a prescription from the doctor. They can either call it into a local pharmacy or you can have it delivered to your home after purchasing it online.

  • How Long Would It Take to Deliver This Drug If I Bought It Online?

    Depending on the dosage amount you ordered and your location, your prescription should arrive in the mail in three to five business days.

  • Is There a Generic Version of Ondansetron?

    Ondansetron is actually the generic version of the brand name, Zofran. It's an antiemetic and a selective 5-HTC receptor antagonist, meaning it actively works to treat any nausea, vomiting, or migraines, especially after surgery or chemotherapy.

  • Who Makes This Drug?

    This drug was created by the London-based company, GlaxoSmithKline. It became available in the United States in September 1987 and was approved by the FDA in January 1991. It's since been used by doctors all around the nation.

  • Do I Need to Take Ondansetron with Food?

    You can take this medication with or without food and it should still provide the same effects. If you're taking it to help with symptoms after your surgery, take it right before your surgery or treatment starts. If you're taking the regular capsules, take it with a full glass of water.

  • Does Ondansetron Interact with Aspirin?

    If you feel your migraine is still strongly affecting you and need a little extra help, low strength aspirin is not known to interact negatively with Ondansetron. As always, you should consult your doctor before taking aspirin or any other medication with Ondansetron.

  • Does Odansetron Expire?

    Yes, it does have an expiration date on the back of the bottle or pack. Don't take it after the expiration date, as it might not work as well and may cause serious side effects.

  • How Does Nurx Work?

    Nurx is a telehealth platform offering easy online access to doctors and seamless delivery of medications. No more time-consuming trips to the clinic and no more frantic pharmacy runs. We put you in control of your own health, empowering you to get the care you need, when you need it. From diagnosis to delivery of prescriptions, we make every part of getting healthy and staying healthy, better.For more information and to signup, visit www.nurx.com and follow us @nurxapp on Twitter and Instagram.  

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