Rx

Twirla®

Twirla®† is a combination hormonal birth control patch.

Birth control Icon Birth control
Patch

$150 for a 3-month supply

As low as $0/month with insurance

Medications shipped and billed according to your selected plan. Medication costs vary based on prescribed treatment and applicable insurance coverage. Not all insurance plans are accepted. Additional costs apply, including a medical review and support fee. This treatment requires an online consultation with a Nurx medical provider.

A person with curly hair and a denim jacket looks upward, surrounded by lush greenery, capturing a moment of serenity. Loryna might find inspiration in such a tranquil setting.

What is Twirla® used for?*

  • Prevents pregnancy
  • Reduces pain from periods
  • A better option for those seeking an alternative to a daily pill
Find my treatment

The science behind it

Fact 01

Releases estrogen and progestin

Twirla® releases estrogen and progestin to prevent ovulation and pregnancy.

Fact 02

Interrupts fertilization and implantation

To prevent pregnancy, this medication thickens cervical mucus to stop sperm from reaching an egg (fertilization) and induces changes to the uterine wall to prevent fertilized eggs from attaching (implantation).

Fact 03

Weekly method

Twirla® is just as effective as the pill, and you don't have to remember to take something every day. This medication is a soft patch that you change each week.

Real patient stories

Blurry image of a lush green landscape with mountains, possibly reminiscent of places like Loryna, under a blue sky dotted with clouds.
DID YOU KNOW

45% of Nurx patients

use birth control for reasons other than preventing pregnancy

A woman in a yellow sweater holds a glass of water and a Loryna pill, preparing to take her medication.

How to use

Birth control is most effective when taken consistently and as prescribed.

Drug facts

Tip 1

Twirla® is a birth control patch that prevents pregnancy by inhibiting ovulation

Tip 2

Apply and change the Twirla® patch each week for three weeks.

Tip 3

Go patch-free on the fourth week and have a period.

How Nurx works

1

Request treatment

Complete our online medical consultation, which asks questions about your health history and birth control preferences.

2

Connect with a provider

After evaluating your consultation, a provider licensed in your state will prescribe birth control (if clinically appropriate).

3

Get it delivered

We’ll send a 3-month supply to your doorstep and check in with you to see how it’s working. Pause or cancel anytime.

Under a clear blue sky with wispy white clouds, the tranquility of nature unfolds, reminiscent of the gentle effect Loryna has on life's rhythms.

100%

online expert-level care

2+ million

Nurx patients served

A person wearing headphones and a beige sweater holds a smartphone with a floral case, glancing at an article on Tretinoin Cream.
Why Nurx?

Affordable

Affordable out of pocket pricing

Convenient

Free shipping & pause or cancel anytime

Personalized

Providers help you find the right treatment

Supportive

Unlimited messaging for any questions, anytime

Common questions

  • How does this medication work?

    Twirla® is a birth control patch that gives off hormones that prevent your ovaries from releasing eggs. Twirla® contains a different mix of hormones than the original birth control patch, Xulane. Just like there are many birth control pill formulas that contain different mixes of hormones, now there's a second patch option. For some people, the patch is a great option since it does not need to be taken every day like a pill to be effective — you simply change your patch every week for three weeks, then have a patch-free week at the end of the month when you have a period.

  • What precautions should I take when using this medication?

    It is not recommended to use any patch continuously to skip periods beyond 3 periods in a row. The reason is that patches contain one of the highest doses of estrogen available, and after 3 months of continuous use the level of estrogen in your body increases to a point that the risk of adverse effects like blood clots and stroke increase.

  • What are the side effects of this medication?

    The side effects of the patch are the same as those of other combined hormone option (those with include both estrogen and progestin). Common side effects include irregular bleeding, nausea, headaches, breast tenderness, and bloating. These typically resolve by the third month of use. One side effect specific to the patch is that the adhesive may cause irritation, redness, or a rash. Uncommon but severe side effects include blood clots that could cause a heart attack or stroke.

  • Can I take this medication with other medications?

    It's important to tell your provider if you are taking any other medications or if you have any allergies. Interactions are possible with certain drugs, and you may need a dose adjustment to safely take both medications. If you start using a new medication, check with your provider before stopping or starting any of your current medicines. This includes over-the-counter medications.

  • How is this medication different from other birth control patches?

    Twirla® contains a different type of progestin than Xulane, and since everyone responds differently to hormones, some people may feel better with the change of hormone combination.

    Twirla® is beige and round and a little larger than Xulane, which is square and peach-toned patch.

    For more information about how Twirla® compares with Xulane, click here.

  • Does this medication cause weight gain?

    Any weight gain you experience when starting this medication is likely due to fluid retention, and should decrease after your body adjusts. If you experience significant weight gain or loss after starting a new contraceptive, it's important to let your healthcare provider know.

  • Does this medication help with acne?

    While not originally intended to treat acne, studies have found that some birth control medications can reduce breakouts and inflammation. If you're interested in learning more about what birth control might help your acne symptoms, visit our Birth Control for Acne page to get started.

  • Does Nurx offer birth control to help with medical concerns other than preventing pregnancy?

    Your Nurx medical provider will partner with you to find the best care for your symptoms and medical concerns. As medically appropriate, a Nurx provider may prescribe birth control to help manage symptoms associated with PMS (Premenstrual syndrome) and/or PMDD (Premenstrual dysphoric disorder), or to help with cycle control (delayed period). In some cases, birth control may also be used to help manage symptoms of endometriosis and/or PCOS (Polycystic ovary syndrome), to assist with improving acne. While the use of birth control is considered “off-label” for these listed purposes, a licensed Nurx clinician may prescribe birth control if they deem doing so medically appropriate.

  • How much does birth control from Nurx cost?

    Consultation
    Anyone who requests a birth control prescription will be charged a $28 consultation fee. Please note that at this time, we do not submit claims to insurance for the medical consult fee.

    Medication
    For those with health insurance, your prescription will be free in most cases if it is covered by your health insurance, and we accept your plan. Insurance companies set the “copay” for prescriptions and depending on your plan and the prescription, this will usually be $0. Please connect with your insurance company if you would like to learn more about your copay. If you do have a copay, Nurx will authorize a $30 hold at checkout. If your copay is over $30, you will receive a notification to approve the updated amount.

    Support Fee
    Nurx will charge a flat $3 support fee each month one or more of your orders are processed. This fee covers your unlimited, on-demand access to our customer care team as well as certain processing fees. This fee will only be charged once in any month, even if you have multiple orders processed that month. This fee applies whether the order is filled through Nurx or at your local pharmacy. If your order is filled via Nurx, the support fee is billed at the time of fulfillment. If your prescription is sent to a local pharmacy, a support fee will be applied at that time. In the future, the support fee will be applied on a cadence that matches your medication refill cadence.

  • Does Nurx accept insurance for birth control?

    Yes, we accept most forms of private health insurance for medications. If you’d like to know if we accept your health insurance plan, please connect with our team at [email protected]. Please note that at this time, we do not submit claims to insurance for the medical consult fee.
    Nurx does not accept any federal or state government insurance plans, such as Medicare, Medicaid, Tricare, or any of their affiliated managed care plans, nor can Nurx service such patients. We recommend that you find a local provider in your community that participates in your government payer program.

A person with long dark hair smiles at the camera, wearing a purple turtleneck sweater. The background is a blurred sky.
DR. NAVYA MYSORE, MEDICAL DIRECTOR

Meet your medical team

Navya Mysore, MD is the Medical Director of Women’s Health at Nurx. Dr. Mysore is a women's health expert with a background in primary care who advises the Nurx medical team to provide the highest quality of care for women through telehealth.

Twirla® (levonorgestrel/ethinyl estradiol patch), Rx only, is an oral contraceptive used to prevent pregnancy. This drug may cause side effects, including headaches, irregular and/or heavy uterine bleeding, dysmenorrhea, nausea and/or vomiting and back pain. If you would like to learn more, please see the full prescription information here. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch: HTTPS://WWW.FDA.GOV/SAFETY/MEDWATCH/default.htm or call 1-800-FDA-1088.

*Individual results may vary.
‡The information provided here is not a substitute for professional medical advice, diagnosis, or treatment. You should not rely upon the content provided here for specific medical advice. If you have any questions or concerns, please talk to your provider.
◊Services not offered in every state. Medications prescribed only if clinically appropriate, based on completion of the required consultation.

Talk to our experts

Not sure if this medication is right for you?

Connect with a Nurx provider for a personalized treatment recommendation.

Exceptional care at every step

At Nurx, we make it easy to get the expert healthcare you deserve. From schedules to health history, everybody is different—so we provide treatment and care that’s personalized to you. Through life’s cycles, changes, and transitions, we’re here to help you make informed choices about your health.

Mockup of the Nurx app actions
Back to top