Rx
Generic Pristiq®

Desvenlafaxine ER

4.8
26,582 Nurx Reviews
Based on all Nurx reviews, not any one product

Desvenlafaxine ER is an antidepressant that may be prescribed to treat major depressive disorder.

Depression Icon Depression
Capsule Icon Capsule

$25/month

As low as $0/month with insurance

Medication shipped and billed every 1 or 3 months.
This treatment requires an online consultation with a Nurx medical provider. Cost may vary based on your insurance coverage, price not guaranteed. Not all insurance plans are accepted. Medication costs vary based on prescribed treatment and applicable insurance coverage and are shipped and billed separately as a 1-month or 3-month supply. Additional costs apply, including a monthly medication management fee.

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How desvenlafaxine ER treats depression*

  • Increases serotonin and norepinephrine levels in the brain
  • May improve how you feel when you have depression
  • Can increase energy level and feelings of well-being
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Did you know?

21 million US adults

have experienced at least one major depressive episode

Real patient stories

The science behind it

Fact 01

Restores balance

This medicine regulates serotonin and norepinephrine levels in the brain.

Fact 02

SNRI antidepressant

This medication is part of a class of drugs called serotonin-norepinephrine reuptake inhibitors.

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How to use desvenlafaxine ER

While some notice an improvement in symptoms within 2 weeks, it may take several weeks to experience the full benefits of this medicine.

Drug facts

STEP 1

Take as prescribed by your provider.

STEP 2

May be taken with or without food.

STEP 3

Depending on how you respond to treatment, your provider may recommend adjusting your dosage.

How Nurx works

1

Request treatment

Complete our online medical consultation, which asks questions about your health history and mental health symptoms.

2

Connect with a provider

After evaluating your consultation, a provider licensed in your state will prescribe treatment (if clinically appropriate).

3

Get it delivered

We’ll send a 1 or 3-month supply to your doorstep and check in with you to see how it’s working. Pause or cancel anytime.

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100%

online care

2+ million

Nurx patients served

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Why Nurx?

Affordable

Quality treatment at an attainable price

Convenient

Easy refills & shipping to your door

Personalized

Providers help you find the right treatment

Supportive

Unlimited messaging for any questions, anytime

Common questions

  • What is desvenlafaxine ER?

    Desvenlafaxine ER is used to treat major depressive disorder. For some, desvenlafaxine ER can help decrease disruption to social life, work, leisure activity, family life, and home responsibilities. It may improve your mood, energy level, and feelings of well-being.

  • How does desvenlafaxine ER work?

    Desvenlafaxine ER belongs to a group of drugs called serotonin-norepinephrine reuptake inhibitors (SNRIs). It works by increasing the amounts of serotonin and norepinephrine in the brain. These chemicals are thought to play a part in depression and other conditions. By working on these chemicals, desvenlafaxine ER may improve how you feel when you have depression.

  • What are the side effects of desvenlafaxine ER?

    Common side effects include nausea, sweating, constipation, dizziness, and weight or appetite changes. Some desvenlafaxine patients also experienced trouble sleeping, changes in libido, and sexual dysfunction. Patients are encouraged to speak with their provider if they feel that these side effects are having a negative impact on their daily lives.

  • How do I take desvenlafaxine ER?

    Desvenlafaxine ER should be taken as prescribed by your healthcare provider. It’s important to follow your doctor’s directions for taking desvenlafaxine ER. If you miss a dose, take it as soon as you remember—unless it’s almost time for your next dose. In that case, skip it and take your next scheduled dose. Your provider may start you on a low dose of this medication and gradually increase your dose.

  • Can I take desvenlafaxine ER with other medications?

    Yes, you can take desvenlafaxine ER with other medications. Make sure to check for interactions with your healthcare provider before beginning treatment.

  • Are there any risks when taking desvenlafaxine ER?

    Patients should be aware that they may experience increased heart rate while taking desvenlafaxine ER, especially when they are beginning a new prescription. If you have any heart conditions or are currently on medication for your heart, it’s a good idea to tell your healthcare provider before starting desvenlafaxine ER. Let your provider know if you have high blood pressure, bleeding problems, or seizures. Talk to your provider if you are breastfeeding or plan to breastfeed before taking desvenlafaxine ER.

  • How quickly does desvenlafaxine ER work?

    In clinical trials, desvenlafaxine ER was shown to provide depression relief in as little as two weeks. However, some people may not notice improvement until they've been taking desvenlafaxine ER for several weeks. It’s important to keep taking your medication each day so that you can get maximum relief from your symptoms. It is important to not stop desvenlafaxine ER suddenly as this can cause withdrawal symptoms. If you plan to discontinue use of this medication, talk to your provider about a plan to taper your dose gradually.

Please note: Nurx does not provide therapy or counseling. Nurx is not available for crisis response. If you are experiencing a mental health crisis, please contact 911 or go to your nearest emergency department. IF YOU ARE CONTEMPLATING SUICIDE, CONTACT 911 OR CALL/TEXT THE NATIONAL SUICIDE PREVENTION LINE AT 988. These services are available 24/7.

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DR. GABRIELLA FARKAS, MEDICAL DIRECTOR

Meet your medical team

Gabriella Farkas, MD PhD is the Medical Director for Nurx’s mental health services. Dr. Farkas is a board-certified psychiatrist who advises the Nurx medical team on how to provide the highest quality of care for mental health conditions through telehealth.

†Desvenlafaxine ER tablets (25mg, 50mg, & 100mg), Rx only, treats major depressive disorder. Desvenlafaxine ER may also cause side effects including but not limited to nausea, sweating, constipation, dizziness, and weight or appetite changes. If you would like to learn more, see full prescribing information, here. You are encouraged to report negative side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. If you’re experiencing a mental health crisis, please call 911 or go to your nearest emergency department.
*Individual results may vary.
‡The information provided here is not a substitute for professional medical advice, diagnosis, or treatment. You should not rely upon the content provided here for specific medical advice. If you have any questions or concerns, please talk to your provider.
◊Nurx does not provide talk therapy or crisis management. Services not offered in every state. Medications prescribed only if clinically appropriate, based on completion of the required consultation.

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Exceptional care at every step

At Nurx, we make it easy to get the expert healthcare you deserve. From schedules to health history, everybody is different—so we provide treatment and care that’s personalized to you. Through life’s cycles, changes, and transitions, we’re here to help you make informed choices about your health.

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