Tube of Azelaic Acid Gel 15% against a gradient background.
Tube of Azelaic Acid Gel 15% against a gradient background.
Rx
4.8
26,690 Nurx-wide reviews
Rx

Azelaic acid 15%

4.8
26,690 Nurx-wide reviews

Azelaic acid† reduces dark spots and skin discoloration for a more even complexion.*

Dark spots/Melasma Icon Dark spots/Melasma
Topical gel Icon Topical gel

$90 for a 3-month supply

Find my treatment

Medications shipped and billed according to your selected plan. One tube of medication contains a 3-month supply. Medication costs vary based on prescribed treatment. Additional costs apply, including a medical review and support fee.
This treatment requires an online consultation with a Nurx medical provider. If prescribed, they'll check in to ensure your treatment is working.

A woman with long brown hair looks to the side, pondering the effectiveness of Hydroquinone Cream against a plain background.

How azelaic acid treats melasma*

  • Reduces dark spots caused by melasma
  • Reduces hyperpigmentation and uneven pigmentation
  • Reduces skin discoloration
Find my treatment
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DID YOU KNOW?

Safe for sensitive skin

Studies indicate that azelaic acid can be used for reactive and sensitive skin*

Real patient stories

26647 Nurx-wide reviews

See all reviews

Awesome

I've been using nurx for years now, they are great. Even when I had issues with my script or whatever the problem was resolved quickly

Brittany

6/4/2025

Excellent

Customer service is excellent always get your product out in a timely matter. Can't say enough about these guys if you want to try this absolutely do it you will not be disappointed.

Jennifer

4/11/2025

Best decision I've made

Best decision I've made in my adult life. I have STRUGGLED with acne since I was about 14. 10 years later and I'm still battling it. I stumbled across Nurx from a YouTube video. Just as the creator said, it was a super easy process. I have been prescribed Tretinoin for about 6 months now and wow, has it made a difference in my skin. The dermatologists instructions were very clear and precise. It's extremely affordable and words cant describe how happy I am that I found Nurx.

Aliyah

09/10/2024

Clutch

Positively impacted my life for years with access to birth control and acne treatment

Jessa

9/5/2024

Excellent service

I couldn't get my PCP to acknowledge my acne concerns and I spent good money for unfruitful office visits. I ended up firing her and finding a new PCP but in the interim I utilized Nurx services AND Nurx was less expensive!

Jacqueline

9/4/2024

Crazy Adult Acne

The PA that I was in contact with, was very thorough. They did not feel the medication I initially contacted them about was the right fit, and am very pleased so far with what was recommended and perscribed for me. My acne is significantly better. I'm feeling better about being seen, knowing my acne is noticeably better! Thank you!!

Jennifer

7/12/2022

Simple!

Nurx is so simple, easy and convenient!! Just had to answer a few questions about my skin/acne and my medication was delivered to my house fast !! It was billed through my insurance so I didn’t have to pay out of pocket. I would 100% recommend to any one !

Jessica

7/11/2022

Acne medication

The process was easy and not stressful. They were able to help me as I’m waiting to be seen in person by a dermatologist. Seems every time I make an appointment, something comes up and I have to reschedule. But the two medications that have been prescribed have helped my face so much already. My confidence is coming back and my skin is getting better! The oily look is disappearing and a lot of the redness is gone. I’m happy I went through with this brand and took a leap of faith to try it.

Taylor

7/7/2022

So helpful

I was really frustrated by my acne. I am so happy I was able to get professional help from my phone. They made it so easy. I trust their advice and even following the routine for a week I've seen improvement.

Alyssa

7/6/2022

Acne Medication

Price was decent, response time was almost a month, and it’s to soon to know how the medication is working for me.

Ashley

6/27/2022

The science behind it‡

Find my treatment
Fact 01

Anti-inflammatory

Hyperpigmentation can be caused by inflammation in the skin, and azelaic acid has antimicrobial properties to reduce this.

Fact 02

Part of a balanced routine

If you've been using hydroquinone to treat melasma for 3-6 months, your Nurx provider may recommend switching to azelaic acid to give your skin a break.

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Find my treatment
A person applies a small amount of hydroquinone cream to the back of their hand near a sink area.

How to use azelaic acid‡

Consistency is key to maximizing the effectiveness of your melasma treatment.

Drug facts

Tip 1

Apply twice a day if tolerated (we recommend applying after you wash your face in the morning and at night).

Tip 2

Before sun exposure, apply sunscreen as azelaic acid can make skin more sensitive to the sun.

Tip 3

If you have sensitive skin, try applying azelaic acid just once a day and then gradually increase to twice a day.

How Nurx works◊

Find my treatment
1

Request treatment

Complete our online medical consultation, which asks questions about your health history and skin concerns.

2

Connect with a provider

After evaluating your consultation, a provider licensed in your state will prescribe treatment (if clinically appropriate).

3

Get it delivered

We’ll send a 3-month supply to your doorstep and check in with you to see how it’s working. Pause or cancel anytime.

Find my treatment
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100%

online expert-level care

2+ million

Nurx patients served

A person wearing headphones and a beige sweater holds a smartphone with a floral case, glancing at an article on Tretinoin Cream.
Why Nurx?

Affordable

Affordable out of pocket pricing

Convenient

Free shipping & pause or cancel anytime

Personalized

Providers help you find the right treatment

Supportive

Unlimited messaging for any questions, anytime

Common questions‡

See all FAQs

  • What does azelaic acid do to your skin?

    Azelaic acid helps reduce pigmentation by inhibiting melanin production, leading to a more even complexion.

  • Does azelaic acid have any side effects?

    Common side effects include mild redness, dryness, itching, or a stinging sensation at the application site. These effects are usually temporary and can be addressed by decreasing the frequency of application to once a day or every other day.

  • Is it bad to use azelaic acid every day?

    Azelaic acid is generally safe to use daily, but if you have sensitive skin you may try to start using it every other day to allow your skin to adjust. If well-tolerated, you can gradually increase to daily or twice daily use.

  • How long does it take azelaic acid to work?

    Results from azelaic acid typically take 4-8 weeks to become noticeable. For significant improvement in skin conditions like melasma and acne, it may take up to 3-6 months.

  • What skin conditions does azelaic acid help with?

    Azelaic acid is effective for treating acne, rosacea, and melasma. It also helps with post-inflammatory hyperpigmentation from acne and overall skin texture.

  • What precautions should I take when using azelaic acid?

    Apply azelaic acid to clean, dry skin and follow up with sunscreen during the day, as it may increase sensitivity to sunlight. Avoid using it with harsh exfoliants or other potentially irritating skincare products. Rarely, azelaic acid has been reported to exacerbate asthma.

  • Can I use this medication if I am pregnant, breastfeeding, or trying to conceive?

    Azelaic acid is safe for use during pregnancy and breastfeeding.

  • How much does melasma treatment from Nurx cost?

    Consultation
    Anyone who requests melasma treatment will be charged a $40 consultation fee. Please note that at this time, we do not submit claims to insurance for the medical consult fee.

    Medication
    Medication prices for melasma range from $50-$90 for a three-month supply, and are not covered by insurance. Shipping is always free.

    Support Fee
    Nurx will charge a flat $3 support fee each month one or more of your orders are processed. This fee covers your unlimited, on-demand access to our customer care team as well as certain processing fees. This fee will only be charged once in any month, even if you have multiple orders processed that month. This fee applies whether the order is filled through Nurx or at your local pharmacy. If your order is filled via Nurx, the support fee is billed at the time of fulfillment. If your prescription is sent to a local pharmacy, a support fee will be applied at that time. In the future, the support fee will be applied on a cadence that matches your medication refill cadence.

  • Does Nurx accept insurance for melasma treatment?

    These medications are not covered by insurance and are only available with out-of-pocket pricing.

See all FAQs
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DR. PETER YOUNG, MEDICAL DIRECTOR

Meet your medical team

Peter Young, MD is the Medical Director for Nurx’s Dermatology specialty. Dr. Young is a board-certified dermatologist who advises the Nurx medical team on how to provide the highest quality of care for dermatology conditions through telehealth.

†Azelaic acid gel 15%, Rx only, has not been approved by the FDA as safe and effective to treat melasma, however studies have shown its effectiveness for treating hyperpigmentation associated with hyperpigmentation. Azelaic acid gel 15% may also cause side effects including skin burning, itching, or dryness. By providing this content, Thirty Madison, Inc. in no way supports or endorses the use of this product for such condition(s). Such determination must be made by a licensed clinician who may prescribe Azelaic acid gel 15% because in their clinical judgment, use of the product is medically appropriate.
*Individual results may vary.
‡The information provided here is not a substitute for professional medical advice, diagnosis, or treatment. You should not rely upon the content provided here for specific medical advice. If you have any questions or concerns, please talk to your provider.
◊Services not offered in every state. Medications prescribed only if clinically appropriate, based on completion of the required consultation.

Talk to our experts

Not sure if this medication is right for you?

Connect with a Nurx provider for a personalized treatment recommendation.◊
Explore treatment options

Exceptional care at every step

At Nurx, we make it easy to get the expert healthcare you deserve. From schedules to health history, everybody is different—so we provide treatment and care that’s personalized to you. Through life’s cycles, changes, and transitions, we’re here to help you make informed choices about your health.

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