Ketoconazole 2% Shampoo

COMMON USES: Ketoconazole 2% shampoo is FDA-approved to treat tinea versicolor, but providers may prescribe it to help manage dandruff and support healthy hair growth by reducing scalp inflammation. Ask your health care provider or pharmacist if you have questions.

HOW TO USE THIS MEDICINE: Apply the shampoo to the damp scalp. Lather, leave in place for 5 minutes, and then rinse off with water.

HOW DO I STORE AND/OR THROW OUT THIS DRUG? Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet or drain. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( for more information if you do not have access to a take-back program.

WHAT DO I DO IF I MISS A DOSE? Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.


Ketoconazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • Hair discoloration and abnormal hair texture
  • Removal of the curl from permanently waved hair
  • Itching, skin burning sensation, and contact dermatitis
  • Rash, skin irritation, dry skin, and application site reactions

Patients who develop allergic reactions, such as generalized rash, skin reactions, severe swelling, angioedema, or shortness of breath should discontinue ketoconazole shampoo, 2% and contact their provider immediately.

If you would like to learn more about this medication, please see the full prescription information, here

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088).

WHAT MAY INTERACT WITH THIS MEDICATION? This medication is contraindicated in persons who have known hypersensitivity to the active ingredient (ketoconazole) or excipients of this formulation, which are: coconut fatty acid diethanolamide; disodium laureth sulfosuccinate; FD & C Red No. 40; hydrochloric acid; imidurea; laurdimonium hydroxypropyl hydrolyzed collagen; PEG-120 methyl glucose dioleate; purified water; sodium chloride; sodium hydroxide; and sodium lauryl ether sulfate.

This is not an exhaustive list of all potential drug interactions. Please inform your Nurx provider regarding all of your current medications.

Ketoconazole shampoo 2% should not be used in patients who are pregnant, breastfeeding, or attempting to conceive.

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