Tretinoin Anti-Aging Cream .05% (Retin-A) Image

Tretinoin Anti-Aging Cream .05% (Retin-A)

Tretinoin Anti-Aging Cream .05% (Retin-A) Image

Product details

Sun-soaked days outdoors are the best, but they’re not the best for your skin — sun damage shows up down the road as fine lines, wrinkles, discoloration and dullness. Luckily, the topical medication tretinoin is proven to reverse skin aging related to years of fun in the sun.

Retinoid creams like tretinoin increase production of collagen and hyaluronic acid and accelerate turnover of the skin’s top layer. Over time this reduces the appearance of fine lines, wrinkles, uneven pigmentation, dark spots, age spots, rough texture, and can create a rosy glow.

Medication type:

Recommended for:

✓ Reversing and preventing fine lines, wrinkles, age spots and dark spots

✓ Reducing hyperpigmentation and uneven pigmentation

✓ Reversing skin aging related to sun damage

✓ Reducing visible signs of aging


Price with InsuranceOut-of-Pocket Price
Not applicableAs little as $30 per month for the medication


We also charge a $15 medication consultation, which includes unlimited access to our medical team for a full year.

Please note: Tretinoin medication is supplied in a 3-month supply, which costs $90 total.

Brand name:

Related product:
Tretinoin Anti-Aging Cream 0.025%, Tretinoin Anti-Aging Cream 0.1%


For our refund and return policy, please see our terms of use.

Additional Details

  • Unclogs pores
  • Reduces number and severity of acne breakouts
  • Smooths skin
  • Brightens complexion
  • Improves the appearance of fine lines and wrinkles
  • Lightens acne-related discoloration
  • Stimulates collagen and elastin production
Active Ingredients
  • Tretinoin 0.025% or 0.05%
  • Increased photosensitivity.
  • Increased risk for skin peeling or flaking.
  • Increased risk for skin irritation.
  • Temporary lightening or darkening of the skin.





  • How Does Tretinoin Cream Work?

    Tretinoin is a synthetic form of Vitamin A. Tretinoin stimulates cell growth and rapid exfoliation to reveal fresh, new skin. Tretinoin also decreases the buildup of dead cells that can clog pores.

    Tretinoin should be used once a day, preferably as part of your bedtime routine. To use Tretinoin Cream, simply wash your hands and skin with a mild facial cleanser. To reduce irritation, be sure to allow your skin to dry for 20 to 30 minutes after washing. You only need to use a thin layer of Tretinoin to reap the benefits. Using too much can cause excessive dryness and flaking. Avoid getting Tretinoin in your eyes, ears, mouth, and nose. Tretinoin should be stored tightly closed, at room temperature, in its original container.

  • Is Tretinoin Cream Easy To Get?

    Tretinoin Cream 0.025% or 0.05% is available in most pharmacies. As the generic equivalent of pricey Retin-A, Atralin, and Avita, Tretinoin provides the same great results at a much lower price. Because it is stronger than over-the-counter retinol products, Tretinoin Cream is available only with a prescription. After reviewing your medical history, Nurx medical providers will prescribe Tretinoin Cream if appropriate. With Nurx, your prescription arrives through the mail privately, safely, and discreetly.

    Tretinoin Cream is covered by most insurance plans as well as Medicare Part D and Medicare Advantage. Nurx accepts many private insurance plans, and our list is always expanding.

  • What Precautions Should I Take When Using Tretinoin Cream?

    As with any prescription medication, discuss all of your medications, allergies, and treatment options with your doctor or a Nurx provider before using Tretinoin Cream. If your skin is irritated or sunburned, you may need to allow your skin to heal before beginning treatment. Your doctor or a Nurx provider can advise you on the proper time to start adding Tretinoin to your skin care regimen. 

    Tretinoin Cream can make your skin more sensitive to ultraviolet light. Using Tretinoin at night lowers your risk of sun damage. During the daylight hours, protect your skin from sunburn and sun damage by wearing protective clothing, hats, and sunscreen with an SPF of 30 or higher. Avoid spending time in tanning beds and under sunlamps. If you get sunburned or your skin becomes extremely red or blistered, contact your healthcare professional immediately.

    Some Tretinoin users experience new or increased sensitivity to extreme weather conditions, such as low temperatures or high winds. Wear protective clothing to stay comfortable during cold or windy weather.

    When using Tretinoin, your facial cleansers and cosmetics should be gentle, non-abrasive, and non-drying. Using a good moisturizer will help your skin stay supple and comfortable. Confused about which products to use?  Your healthcare professional can help you choose products that maximize the benefits of Tretinoin Cream and minimize unpleasant side effects. 

    Tretinoin has not been adequately studied in pregnant or breastfeeding women. If you are pregnant or breastfeeding, consult with a healthcare professional to determine if Tretinoin Cream is right for you.

  • Does Tretinoin Cream Have Any Known Side Effects?

    Like every topical retinoid, Tretinoin use may cause side effects. Most of the side effects caused by Tretinoin are mild and include drying, flaking, or peeling skin. You may also experience a mild, temporary stinging or warming sensation when applying Tretinoin. Skin treated with Tretinoin is more prone to sunburn and sun damage. Repeated use of Tretinoin may also cause temporary lightening or darkening of the skin. Most people using Tretinoin find that side effects lessen as their skin adjusts to treatment. If you find these mild side effects unpleasant, rest assured that all of them completely disappear when Tretinoin is no longer used.

    Although severe reactions are uncommon, possible serious side effects include itching, hives, and pain. These side effects are usually a result of an allergic reaction. Although scary, such reactions to Tretinoin are very rare. If you are allergic to drugs that contain Vitamin A (such as Isotretinoin), you may be at higher risk for an allergic reaction.

  • Can I Use Tretinoin Cream With Other Medications?

    Tretinoin generally is compatible with other medications. To prevent excessive dryness and irritation, avoid using facial cleansers, toners, and cosmetics that contain sulfur, salicylic acid, or resorcinol. Never combine Tretinoin with products containing benzoyl peroxide, as they diminish Tretinoin's effectiveness and can result in dryness.

    Topical products that may interact with Tretinoin include perm solutions, medicated cleansers, exfoliating soaps, alpha hydroxy acid, glycolic acid, and products that contain alcohol, lime, or menthol. Using these products with Tretinoin can cause excessive redness, irritation, and peeling.

    You should avoid using Tretinoin if you are currently taking fluoroquinolones, tetracyclines, thiazide water pills, sulfa drugs, and phenothiazines. The combination of Tretinoin and these drugs can increase your skin's sensitivity to sunlight.

  • How Do I Get a Prescription for Tretinoin Cream Through Nurx?

    Getting your prescriptions with us could not be simpler. Select your medication, answer a few questions, and enter any insurance information you have. No insurance? No problem. You can still get the medications you need at a great price. One of our Nurx medical providers in your home state will review your prescription request and write your prescription, if appropriate. Your medication is then quickly and discreetly delivered to your home.

  • Can I Buy This Drug Online Through Nurx?

    Yes! You can get your Tretinoin cream 0.025% or 0.05% quickly and easily through Nurx.

  • How Long Would It Take To Deliver This Drug If I Bought It Online?

    After a review by our Nurx medical team, we'll ship your Tretinoin prescription in 72 hours or less. Your prescription is shipped for free using USPS 1-3 day priority mail. You should receive your Tretinoin 3-5 business days after your prescription request is complete. Expedited shipping is available; just call us at 1-800-321-NURX between 9 a.m. and 5 p.m. EST, Monday through Friday.

  • Who Makes Tretinoin Cream?

    Tretinoin Cream is made by Valeant Pharmaceuticals International, Inc. for Spear Dermatology Products.

  • Which Tretinoin Cream is right for me?

    Your doctor or one of our Nurx medical professionals can help you figure out if the 0.025% or 0.05% cream is best for you based on your symptoms and medical history.

  • Does Tretinoin expire?

    All prescription retinoids come with an expiration date. Although not dangerous to use, expired Tretinoin may not be as effective.

  • Does Tretinoin help with wrinkles?

    Because it speeds up cell turnover, Tretinoin can make your skin look brighter and younger. Tretinoin also increases your skin's production of collagen, a vital component in young, healthy skin.

  • Does Tretinoin help with acne scars?

    If breakouts have left you with uneven, bumpy skin and scars, Tretinoin can help. Tretinoin helps flatten acne scars and lighten dark patches, making scars less noticeable. Tretinoin is most effective on newer, smaller acne scars.

  • Does Tretinoin bleach fabrics?

    No. Unlike products that contain benzoyl peroxide, your clothes, towels, and sheets are safe from bleaching with Tretinoin.

  • How long before I see improvement with Tretinoin?

    If you are new to Tretinoin, you may be surprised to experience more blemishes after using the product for three to six weeks. This is a normal part of the skin renewal process. Don't give up! Most people see a noticeable improvement in their skin after using Tretinoin for six to 12 weeks.

  • How Does Nurx Work?

    Nurx is a telehealth platform offering easy online access to doctors and seamless delivery of medications. No more time-consuming trips to the clinic and no more frantic pharmacy runs. We put you in control of your own health, empowering you to get the care you need, when you need it. From diagnosis to delivery of prescriptions, we make every part of getting healthy and staying healthy, better.

    For more information and to sign up, visit and follow us @nurxapp on Twitter and Instagram.

Back to top