No, in order for a generic substitution to be made it must be proven to the FDA to be the same thing. These products have the same active ingredients, dosage forms, strengths, routes of administration and conditions of use as the brand name drugs, and are bioequivalent (meaning they act the same in the body) if deemed substitutable by the FDA. They will be equally efficacious. Generic drugs have to meet the same requirements that brand-name drugs meet, in order to gain FDA approval and be sold in the US. This does not mean that you may not have any side effects to a specific pill. Every woman may respond differently to a birth control. The pill your roommate takes and loves, may not work well for you. It may take some trial and error to find you a birth control that you like, but we can try to help you manage side effects and work together to do that.