As with any medication you start, you should speak with your doctor about possible interactions between other medications you take. This includes any over-the-counter medicines, vitamins, and herbal supplements. Propranolol, like many other beta-blockers, comes with some extra precautions, especially concerning other medications. Before taking Propranolol, let your doctor know if you're taking any medications like the following:
Antihistamines.
Sedatives.
Tranquilizers.
Sleeping aids.
Prescription pain medication.
Narcotics or barbiturates.
Muscle relaxants.
Anticonvulsant medicines.
Since Propranolol can affect these types of central nervous system depressant drugs, it's best to let your healthcare provider know if you're planning to have any medical procedures, including dental procedures, that require anesthetics before taking Propranolol.
Even though studies show Propranolol doesn't cause harm during pregnancy, it's still important to talk to your doctor before taking Propranolol if you're pregnant or planning to become pregnant. On the other hand, Propranolol can pass through breastmilk, so if you're breastfeeding, your doctor may help you find another migraine treatment option.
You'll also need to discuss any medical problems or history of medical issues you have with your doctor before taking Propranolol, including:
Muscle disorders.
Low blood sugar.
Low blood pressure.
Depression or anxiety.
Kidney or liver disease.
Thyroid disorders.
Circulatory problems.
As with any new prescription, monitor any concerns you have when you start taking your medication and stay on top of regular checkups to help your doctor evaluate the success of your migraine treatment.