Product details

Triphasil-28 is a combination oral contraceptive that is taken by mouth at the same time every day. This medication comes in a kit of 28 tablets with varying doses of the female hormones estrogen and progestin. These hormones are combined to primarily stop ovulation, the release of an egg from the ovary. If ovulation should take place, Triphasil-28 works to create changes to thicken vaginal fluid and impede the progress of sperm to penetrate an egg (fertilization). If sperm were to fertilize an egg, Triphasil-28 further acts to change the lining of the uterus to keep fertilized eggs from attaching to the uterine wall (implantation). Fertilized eggs are safely passed out of the body when they fail to attach.

Our team at Nurx™ can prescribe Triphasil-28 at special request, or can offer the generic equivalent Trivora for as low as $0 with insurance or as little as $15 without insurance.

Additional Details

  • Less painful periods
  • Improve acne
  • Decreased risk of developing ovarian cysts
  • Decreased risk of developing ovarian cancer with long-term use
  • Minimal weight change
  • Reduce headache frequency
  • Lighter period flow
  • Regular
  • 21 active + 7 inactive
Active Ingredients
  • Levonorgestrel (progestin) [0.50, 0.075, 0.125 mg]
  • Ethinyl estradiol (estrogen) [0.030, 0.040, mg]
  • Breast cancer and breast cancer treatment
  • Blood clotting disorders
  • Hypertension
  • Heart disease
  • Hepatitis C treatment
  • Cigarette smoking, especially women over 35





  • How is Triphasil-28 Used?

    A kit of Triphasil-28 includes 28 color-coded tablets containing different amounts of estrogen and progestin. It's important to take Triphasil-28 as directed for it to work correctly and effectively.

    The Triphasil-28 regimen is as follows:

    • Take the brown tablets containing 0.050 mg levenorgestrel (progestin)  and 0.030 of ethinyl estradiol (estrogen) for six days.
    • Take the white tablets containing 0.075 levenorgestrel and 0.40 mg ethinyl estradiol for five days.
    • Take the yellow tablets containing 0.125 mg levenorgestrel and 0.030 mg ethinyl estradiol for ten days.
    • Take the green tablets containing inert ingredients for the remaining seven days.

    While you're taking the final seven green tablets, you should have your period. Begin the next pack of Triphasil-28 whether or not your period starts.

    In addition to birth control, Triphasil-28 offers other benefits such as acne treatment. Triphasil-28 can help regulate your periods and make periods lighter and less painful. With long-term use, Triphasil-28 may help prevent the development of ovarian cancer.

    Store Triphasil-28 in a cool, dry place where it's easy for you to remember to take your pill at the same time each day.

  • Is Triphasil-28 Easy to Get?

    Triphasil-28 is a prescription medication that will require a consultation with your doctor. Triphasil-28 is available at most pharmacies and retails between $55-$80 per 28-day pack. Your insurance may cover all or part of your medication, contact your insurance provider to find out if your medication is covered. If you don't have insurance, contact one of our Nurx team members to discuss your options, including generic alternatives to Triphasil-28.

  • What Precautions Should I Take Before Using Triphasil-28?

    When introducing a new medication, consider your current conditions, medications, and upcoming procedures to determine if Triphasil-28 is the right choice for you.

    Oral contraceptives can elevate blood pressure, increasing the risk for heart disease. Women with significant hypertension and women over 35 who smoke are cautioned against using oral contraceptives. Diabetic women are advised to monitor blood sugar levels carefully while taking oral contraceptives. Talk to your doctor about Triphasil-28 since triphasic contraception may have less impact on blood pressure and blood glucose than other hormone combinations.

    The use of combination oral contraceptives may elevate liver enzymes. Women who are in treatment for Hepatitis C are advised to wait a few weeks following the completion of treatment before starting Triphasil-28.

    Allergic reactions to Triphasil-28 are rare. If you experience symptoms like rash, swelling of the face or throat, or difficulty breathing, you may be having an allergic reaction. Seek medical attention if you develop symptoms of an allergic reaction.

    Contact lens wearers may experience discomfort or intolerance to their lenses while taking Triphasil-28. Talk to your vision care specialist about your lenses and contraceptive compatibility.

    Triphasil-28 can interfere with test results. If you are scheduled for procedures or lab tests, consider waiting until procedures are complete before starting Triphasil-28.

    While Triphasic-28 is effective birth control, it does not protect against sexually transmitted diseases or infections.

  • Are There Any Known Side Effects?

    When introducing a new medication, side effects are pretty common. Most women report breast tenderness, fluid retention, and spotting as common side effects. For women who experience nausea or vomiting while taking Triphasil-28 , it's a good idea to take this medication with a meal or at bedtime to avoid compromising the effectiveness of Triphasil-28.

    Although they are rare, serious side effects have been reported as mood swings, severe abdominal pain, or yellowing of the skin. Notify your doctor if you experience serious effects like pain in the jaw or chest, confusion, or sudden dizziness while taking Triphasil-28.

  • Can I Take Triphasil-28 With Other Medications?

    Speak to your healthcare provider about medications and supplements you're taking since oral contraceptives can interact with certain medications. Some medications may reduce the amount of hormone in your body, check with your doctor before beginning Triphasil-28.

    Triphasil-28 can interfere with treatments for breast cancer and Hepatitis C. Supplements like St. John's wort can reduce the amount of hormone in your body. Some over-the-counter medications like acetaminophen may interact with oral contraceptives.

  • Can I Buy Triphasil-28 Online Through Nurx?

    We can get Triphasil-28 for you by special request. Contact the Nurx team to learn more about Triphasil-28 and how you can get started with this contraceptive medication.

  • How Long Would it Take to Deliver Triphasil-28 if I Bought it Online?

    We do our best to get your medication to you as discreetly and quickly as possible, often within a week. We can deliver your medication to your mailbox, or you can choose to pick it up from your local pharmacy. Special requests may take slightly longer.

  • Is There a Generic Version of Triphasil-28?

    Yes. Generic versions of Triphasil-28 include TrivoraMyzilra, Levonest, and Enpresse.

  • Who Makes Triphasil-28?

    Triphasil-28 is manufactured by Phizer and distributed by Wyeth Pharmaceuticals.

  • What is the Benefit of Triphasic Birth Control?

    Triphasic birth control may offer better regulation of periods and have less effect on blood pressure and blood glucose than other combination oral contraceptives. Triphasic birth control may lessen headaches and breast tenderness. Talk to your doctor or one of our Nurx representatives to learn more about how triphasic birth control may be beneficial to you.

  • Does Triphasil-28 Stop Periods?

    Not as a rule, no. When you first start taking Triphasil-28 you may encounter spotting or breakthrough bleeding during the first few months of use while your body adjusts to your medication. If your period doesn't regulate after a few months of use, consult with a healthcare professional to discuss other contraceptive options that might work better for you.

  • How Long Does it Take for Triphasil-28 to be Effective?

    Triphasil-28 will begin working when you start taking it. The key to achieving 99% effectiveness is to take Triphasil-28 correctly and consistently. Take Triphasil-28 at the same time every day and try not to allow more than 24 hours between doses. If you're concerned about the effectiveness of Triphasil-28 when first starting, or if you missed more than one dose, consider using backup birth control until your next cycle. Put your smartphone to work and set a reminder so you don't forget to take your meds.

  • How Does Nurx Work?

    Nurx is a free platform offering easy online access to doctors and seamless delivery of medications. No more time-consuming trips to the clinic and no more frantic pharmacy runs. We put you in control of your own health, empowering you to get the care you need, when you need it. From diagnosis to delivery of prescriptions, we make every part of getting healthy and staying healthy, better. For more information and to sign up, visit and follow us @nurxapp on Twitter and Instagram.

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